Sexual and asexual reproduction, male and female reproductive systems, the menstrual cycle, fertilisation, the placenta and amnion, contraception, and STIs.
Reproduction ensures the continuation of a species. Two fundamental strategies exist across living organisms.
| Feature | Asexual reproduction | Sexual reproduction |
|---|---|---|
| Number of parents | one | two |
| Gametes involved | no | yes (male and female) |
| Genetic variation | none (offspring are clones) | yes (offspring are genetically unique) |
| Speed | usually faster | slower |
| Examples | budding, binary fission, runners, cuttings | mammals, flowering plants |
Asexual reproduction is advantageous in stable environments where the parent is well-adapted. Sexual reproduction produces variation, which is valuable when environments change.

| Structure | Function |
|---|---|
| Testes | produce sperm and testosterone |
| Epididymis | sperm mature and are stored here |
| Vas deferens | carries sperm from epididymis toward urethra |
| Seminal vesicles | produce fluid rich in fructose (energy for sperm) |
| Prostate gland | adds alkaline fluid to neutralise acidity of vagina |
| Urethra | carries sperm and urine out of the body (not simultaneously) |
| Penis | deposits sperm in the vagina during intercourse |
Testosterone is produced by the testes from puberty and controls male secondary sexual characteristics (facial hair, deeper voice, muscle development) and sperm production.
Sperm cell adaptations:

| Structure | Function |
|---|---|
| Ovaries | produce eggs (ova) and hormones (oestrogen, progesterone) |
| Fallopian tubes (oviducts) | carry egg from ovary to uterus; site of fertilisation |
| Uterus | muscular chamber; site of fetal development |
| Cervix | lower part of uterus; holds fetus in place; dilates during birth |
| Vagina | receives sperm during intercourse; birth canal |
The menstrual cycle is approximately 28 days and prepares the uterus for a potential pregnancy each month.
| Days | Events | Hormones involved |
|---|---|---|
| 1–5 | menstruation: uterine lining shed | progesterone and oestrogen fall |
| 6–13 | uterine lining rebuilds; egg develops in follicle | FSH rises; oestrogen rises |
| ~14 | ovulation: egg released from ovary | LH surge triggers ovulation |
| 15–28 | uterine lining maintained; if no fertilisation, lining breaks down | progesterone (from corpus luteum) then falls |
Sperm are deposited in the vagina and swim through the cervix and uterus into the fallopian tubes. If an egg is present, one sperm penetrates it — this is fertilisation. The fertilised egg (zygote) divides repeatedly and implants in the uterine wall about 7 days after fertilisation.
The placenta develops where the embryo attaches to the uterine wall. It allows exchange of substances between maternal and fetal blood without the blood mixing:
The umbilical cord connects the fetus to the placenta.
The amnion is a fluid-filled sac that surrounds and protects the developing fetus. Amniotic fluid cushions the fetus against physical shocks, prevents desiccation, and allows the fetus to move freely during development.
| Method | Type | How it works |
|---|---|---|
| Condom | barrier | physical barrier; also protects against STIs |
| Diaphragm | barrier | covers cervix; prevents sperm reaching egg |
| Contraceptive pill | hormonal | contains oestrogen/progesterone; prevents ovulation |
| Contraceptive injection / implant | hormonal | releases progesterone; prevents ovulation |
| IUD (coil) | intrauterine device | prevents implantation; some release hormones |
| Vasectomy | surgical | cuts vas deferens; permanent |
| Tubal ligation | surgical | cuts or blocks fallopian tubes; permanent |
| Natural (rhythm method) | behavioural | avoiding intercourse near ovulation; least reliable |
| Infection | Pathogen | Transmission | Treatment / Control |
|---|---|---|---|
| HIV/AIDS | virus (HIV) | unprotected sex, sharing needles, mother to child | no cure; antiretroviral drugs manage symptoms; condoms and not sharing needles prevent transmission |
| Gonorrhoea | bacterium (Neisseria gonorrhoeae) | unprotected sex | antibiotics; condoms; testing and contact tracing |
HIV attacks helper T-lymphocytes, gradually destroying the immune system. AIDS is the late stage when immunity has collapsed and opportunistic infections occur.
HIV is transmitted through blood, semen, vaginal fluids, and breast milk — not through casual contact. An exam question may ask you to distinguish HIV (the virus) from AIDS (the condition that results from advanced HIV infection).